Wide Spectrum Investigation of Stroke Outcome Disparities on Multiple Levels (WISSDOM) "CINGS"


Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- 40-75 years
- prestroke mRS score >2
- African American or White
- Reside in Berkeley, Charleston, Dorchester, Colleton or Georgetown Counties
- Ischemic stroke involving only one hemisphere
- Fugl Meyer score >16 at baseline or Aphasia Quotient in Western Aphasia Battery <93
- no contraindications to research MRI

Exclusion Criteria

- Primary or secondary intracerebral hematoma, or subarachnoid hemorrhage, or subdural/ epidural hematoma; Prisoner; diagnoses of substance addiction (alcohol or illicit drugs)
- Bihemispheric acute ischemic strokes;
- Other concomitant neurological disorders, such as brain tumor, abscess or spinal cord disease affecting language or limb motor function;
- Documented history of dementia prior to index event;
- Patient suffered one or more recurrent stroke during the 12-month follow up period.
- Terminal illness with life expectancy ≤ 1 year
- Currently pregnant
- Brain stem strokes