Weight Approximation in Stroke Before Thrombolysis "WAIST"


Phase N/A Results N/A

Summary of Purpose

Thrombolysis using Alteplase (tPA) is still the only approved specific therapy for acute ischemic stroke (AIS). Current guidelines in western countries recommend an tPA dose of 0.9mg/kg up to a maximum dose of 90mg for patients weighing more than 100kg. However, larger dose-finding rtPA trials for intravenous thrombolysis in AIS are missing. Based on results from research on myocardial infarction only a few open...

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 13 May 2013.

1 Apr 2008 30 Oct 2009 1 Dec 2013 Unavailable 1 May 2013 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Observation: Cohort
  • Perspective: Prospective
  • Sampling: Non-Probability Sample


  • Martin Kohrmann, MD

  • Lorenz Breuer, MD