Vertebral Artery Stenting Trial "VAST "


Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

1. Transient ischaemic attack (TIA) or non-disabling ischaemic stroke of the posterior circulation 2. Symptoms must have occurred in the 180 days preceding randomisation 3. Possibility to perform stenting within two weeks after randomisation 4. Stenosis of the vertebral artery of 50% or greater, diagnosed by both duplex ultrasound and computed tomography (CT-), contrast-enhanced magnetic resonance (MR-), or conventional angiography, and presumed to be of atherosclerotic origin and accessible for endovascular treatment 5. Score on the modified Rankin scale less than or equal to 3 (independent in daily activities, although some help may be needed)

Exclusion Criteria

1. Potential cause of TIA or minor stroke other than stenosis in a vertebral artery 2. Vertebral artery stenosis caused by arterial dissection 3. Previous surgical or endovascular treatment of the stenosis 4. Life expectancy shorter than three years 5. Other serious illness that may confound outcome assessment 6. severe renal impairment, precluding contrast administration7. allergy to iodinated contrast agent8. pregnancy.