Vascular Events In Surgery patIents cOhort evaluatioN - Cardiac Surgery

Recruiting

Phase N/A Results N/A

Trial Description

Worldwide over 2 million adults (>30,000 Canadians) undergo heart surgery annually. Although heart surgery provides important survival benefits, it is associated with potential major complications such as death, stroke, and heart attack. There is promising evidence that measurement of heart injury markers after surgery will identify patients at risk of death or major complications.
This study will determine the current incidence of major complications in a representative sample of 15,000 contemporary adult patients undergoing heart surgery. Knowing the current burden of complications will inform clinicians, administrators, government and granting agencies about resources required to address the problem. This study will also establish the role of measuring heart injury markers to identify important heart injury after heart surgery and the proportion that would go undetected without routine heart injury marker monitoring. This information will facilitate further studies of timely interventions. In summary, the VISION Cardiac Surgery Study addresses fundamental questions that will have profound public health implications given the millions of adults worldwide who undergo heart surgery annually.

Conditions

Trial Design

  • Observation: Cohort
  • Perspective: Prospective
  • Sampling: Non-Probability Sample

Trial Population

Patients who have undergone cardiac surgery who are at least 18 years of age.

Outcomes

Type Measure Time Frame Safety Issue
Primary All-cause mortality at 30-days after surgery 30 days after surgery No
Primary Myocardial injuries that were not identified clinically during the first 5 days after surgery 5 days after surgery No
Primary Composite of vascular death, nonfatal myocardial infarction, nonfatal cardiac arrest, nonfatal stroke, and mechanical assist device 30 days after surgery No
Secondary Composite of vascular death, nonfatal myocardial infarction, nonfatal stroke, and mechanical assist device 30 days after surgery No
Secondary Total mortality 30 days after surgery No
Secondary Vascular mortality 30 days after surgery No
Secondary Myocardial infarction 30 days after surgery No
Secondary Non-fatal cardiac arrest 30 days after surgery No
Secondary Stroke 30 days after surgery No
Secondary Implantation of mechanical assist device 30 days after surgery No
Secondary Cardiac transplant 30 days after surgery No
Secondary Repeat cardiac revascularization procedures 30 days after surgery No
Secondary Congestive heart failure 30 days after surgery No
Secondary New atrial fibrillation 30 days after surgery No
Secondary Pulmonary embolus 30 days after surgery No
Secondary Deep venous thrombosis 30 days after surgery No
Secondary Major bleeding 30 days after surgery No
Secondary New dialysis 30 days after surgery No
Secondary Infection 30 days after surgery No
Secondary Re-hospitalization for a vascular reason 30 days after surgery No
Secondary Chronic incisional pain 30 days after surgery No

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