Urokinase versus r-TPA in Stroke Patients


Phase N/A Results


r-TPA was not superior to urokinase. Recanalization times in the r-TPA groups were similar to that of the urokinase groups in the basilar territory with a median rate of about 120 minutes for both, but in the carotid territory, the urokinase was far superior with a median rate of 60 minutes compared to the median rate of 120 minutes for r-TPA. Rates of recanalization were not significantly different with urokinase having an incomplete recanalization of 8.5% compared to 32.2% in the r-TPA which also had a 3.4% rate of no recanalization.