United Kingdom Transient Ischaemic Attack Aspirin Trial "UK-TIA"

Completed

Phase N/A Results

Results

Analysis by intention-to-treat showed the odds of suffering a major stroke, myocardial infarction or vascular death were not significantly reduced by aspirin treatment (odds reduction 15%, 95% CI 29% odds reduction to 3% odds increase). There was no significant difference between the treatment groups in the composite event of major disabling stroke and/or vascular death or vascular death alone. There was no definite difference between responses to the 300 mg and 1200 mg daily doses, except that the lower dose was significantly less gastrotoxic.