Trial of a Secondary Stroke Prevention Program


Phase N/A Results N/A

Trial Description

The purpose of this study is to determine whether an outpatient program can reduce the risk of recurrent stroke.

Detailed Description

Stroke is a major cause of death and disability. A history of stroke is the strongest predictor of a future stroke. Control of risk factors lowers the risk of future stroke, yet most persons with stroke do not have their risk factors controlled.
In this randomized-controlled trial, we will test whether an outpatient stroke prevention program consisting of group clinics, patient self-management, and telephone care coordination can lower the risk of recurrent stroke by improving patient knowledge, medication adherence, and lifestyle habits. If successful, this program may be adapted to other settings.



  • Stroke prevention care program Other
    Other Names: group clinics; chronic care model; secondary stroke prevention program; nurse practitioner; medication algorithms
    Intervention Desc: Stroke prevention care program consists of group clinics, telephone coordination of care, and tracking of care through registries in the first 7 months after stroke or TIA presentation. A nurse practitioner will follow algorithms to adjust medications and to motivate patients to improve lifestyle habits.
    ARM 1: Kind: Experimental
    Label: Stroke Prevention Program + Usual Care
    Description: Stroke Prevention Care Program + Usual Care. The Stroke prevention care program is in addition, not a substitute for usual care. Persons randomized to this arm are eligible to all care, including care by stroke specialists, while enrolled in the intervention.

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Investigator, Outcomes Assessor)
  • Purpose: Prevention
  • Endpoint: Efficacy Study
  • Intervention: Single Group Assignment


Type Measure Time Frame Safety Issue
Primary Blood pressure control baseline, 3 months, 7 months No
Secondary control of other stroke risk factors including lipids, smoking, and exercise baseline, 3 months, 7 months No
Secondary patient perceptions of care quality baseline, 3 months, 7 months No
Secondary medication adherence baseline, 3 months, 7 months No
Secondary Stroke knowledge baseline, 3 months, 7 months No