Transcranial Direct Current Stimulation (tDCS) and Task-Specific Practice for Post-stroke Neglect


Phase 1 Results N/A

Eligibility Criteria

Inclusion Criteria

- Unilateral hemispheric ischemic stroke or hemorrhagic subcortical stroke ≥3 months post stroke (lesion type and location to be confirmed with MRI)
- Neglect (Virtual Reality Lateralized Attention Test score <18)
- Upper extremity Fugl-Meyer score between 20-56/60
- Inducible motor evoked potential (MEP) of the abductor pollicis brevis (APB) on the affected side using transcranial magnetic stimulation (TMS)
- ≥18 years old

Exclusion Criteria

- History of cortical hemorrhagic stroke
- Severe spasticity (Modified Ashworth Scale score ≥3) in paretic upper extremity
- Severe aphasia limiting participant's ability to follow 2 step directions
- History of seizures
- History of brain tumor
- History of skull defect
- Hardware in skull or spine (e.g. coils, clips)
- Implantable medical device (e.g. pacemaker)
- Metal in body that is not compatible with MRI
- Pregnant (women of child bearing age will be asked if they are pregnant or could possibly be pregnant)
- Unable to travel to Upper Extremity Motor Function Laboratory at the Center for Rehabilitation Research in Neurological Conditions
- Currently enrolled in another study using transcranial direct current stimulation (tDCS) or transcranial magnetic stimulation (TMS)