Transcranial Direct Current Stimulation for Post-Stroke Aphasia

Terminated

Phase N/A Results N/A

Trial Description

This is a randomized, crossover design trial that will compare how anodal transcranial direct current stimulation (tDCS) versus sham tDCS administered during multiple sessions of scripting therapy affects the acquisition and retention of trained scripts.

Trial Stopped: Poor recruitment

Conditions

Interventions

  • Anodal tDCS Device
    Intervention Desc: Anodal transcranial direct current stimulation using the Chattanooga Ionto device
    ARM 1: Kind: Experimental
    Label: Anodal tDCS
    Description: Anodal tDCS over the left posterior language areas during aphasia therapy for 8 one-hour sessions
  • TDCS Device
    Intervention Desc: Anodal transcranial direct current stimulation using the Chattanooga Ionto device
    ARM 1: Kind: Experimental
    Label: Anodal tDCS
    Description: Anodal tDCS over the left posterior language areas during aphasia therapy for 8 one-hour sessions
  • Sham tDCS Device
    Other Names: noninvasive brain stimulation, transcranial direct current stimulation
    Intervention Desc: Sham transcranial direct current stimulation using the Chattanooga Ionto device
    ARM 1: Kind: Experimental
    Label: Sham tDCS
    Description: Sham tDCS over the left posterior language areas during aphasia therapy for 8 one-hour sessions
  • Aphasia therapy Behavioral
    Intervention Desc: Aphasia therapy using a computerized scripting program
    ARM 1: Kind: Experimental
    Label: Anodal tDCS
    Description: Anodal tDCS over the left posterior language areas during aphasia therapy for 8 one-hour sessions
    ARM 2: Kind: Experimental
    Label: Sham tDCS
    Description: Sham tDCS over the left posterior language areas during aphasia therapy for 8 one-hour sessions

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Investigator, Outcomes Assessor)
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Crossover Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary Change in percent correct of trained scripts From Baseline to up to 2 days post-training No
Primary Change in words per minute of trained scripts From Baseline to up to 2 days post-training No

Sponsors