Transcranial Direct Current Stimulation for Improving Gait Training in Stroke

Completed

Phase N/A Results N/A

Trial Description

The purpose of this study is to determine if transcranial direct current stimulation (tDCS)applied over the lower extremity motor cortex in conjunction with functional electrical stimulation assisted gait training (FESAGT) is effective for improving gait in patients with chronic stroke.

Conditions

Interventions

  • Transcranial direct current stim Device
    Intervention Desc: tDCS will be applied using a Life-Tech®, Iontophor PM Deluxe constant current stimulator with carbon rubber electrodes encased in saline (0.9% NaCl) soaked sponges that measure 5 x 5 cm (25cm2) for the anode and 5x7 for the cathode (35cm2). The anodal electrode will be placed over the lower extremity representation of primary motor cortex of the lesioned hemisphere. The cathodal electrode will be placed over the contralateral supraorbital region.
    ARM 1: Kind: Experimental
    Label: transcranial direct current stim
    Description: tDCS will be applied using a Life-Tech®, Iontophor PM Deluxe constant current stimulator with carbon rubber electrodes encased in saline (0.9% NaCl) soaked sponges that measure 5 x 5 cm (25cm2) for the anode and 5x7 for the cathode (35cm2). The anodal electrode will be placed over the lower extremity representation of primary motor cortex of the lesioned hemisphere. The cathodal electrode will be placed over the contralateral supraorbital region.
    ARM 2: Kind: Experimental
    Label: sham tDCS
    Description: Sham stimulation will be performed by turning the stimulator off after the initial sensory experience (30 seconds).

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Outcomes Assessor)
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Parallel Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary change from baseline in ankle dorsiflexion angle during the swing phase of gait baseline, and one week, one month, and six months after intervention No
Secondary change from baseline in slope of cortical recruitment curve baseline, and 1 week, 1 month, and 6 month post intervention No
Secondary change from baseline in Stroke impact scale scores baseline, and 1 week, 1 month, and 6 moths post intervention No

Sponsors