Transcranial Direct Current Stimulation Aided Rehabilitation of Gait in Subacute Stroke


Phase N/A Results N/A

Trial Description

The purpose of this study is to determine if transcranial direct current stimulation (tDCS)applied over the lower extremity motor cortex in conjunction with treadmill training is effective for improving gait in patients with subacute stroke and to evaluate the effect and predictive value of a single session of anodal tDCS.



  • Transcranial direct current stimulation Device
    Intervention Desc: A direct current runs between two electrode positions and affects the excitability of the underlying brain tissue
    ARM 1: Kind: Experimental
    Label: anodal tDCS with treadmill training
    Description: Each subject will receive 4 weeks gait treadmill training at least 3 days per week in combination with anodal transcranial Direct Current Stimulation over the primary motor cortex up to 20 min

Trial Design

  • Masking: Open Label
  • Endpoint: Efficacy Study
  • Intervention: Single Group Assignment


Type Measure Time Frame Safety Issue
Primary Maximal gait speed using the 10-m walking test Baseline and follow up immediately following the 4 weeks intervention No
Secondary Changes in cortical excitability measures Baseline No
Secondary Dynamometry: the maximal isometric force of muscles will be assessed by Biodex System 3 PRO dynamometer Baseline and immediately following the 4 weeks intervention No