Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis "TOACT"


Phase 2/3 Results N/A

Summary of Purpose

Background: Endovascular thrombolysis, with or without mechanical clot removal (ET), may be beneficial for a subgroup of patients with cerebral venous sinus thrombosis (CVT), who have a poor prognosis despite treatment with heparin. Published experience with ET is promising, but only based on case series and not on controlled trials. Objective: The main objective of the TO-ACT trial is to determine if ET...

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 18 January 2016.

1 Sep 2011 15 Sep 2010 1 Dec 2016 1 Jan 2018 1 Jan 2016 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Open Label
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment