Thrombolysis and Deferoxamine in Middle Cerebral Artery Occlusion "TANDEM-1"

Completed

Phase 2 Results N/A

Eligibility Criteria

Inclusion Criteria

- Age 18-80 years old
- Acute Ischemic Stroke on the middle cerebral artery territory
- Treatment with iv tPA in the first 3 hours from symptoms onset

Exclusion Criteria

- Modified Rankin Scale more or equal to 2
- Infectious, inflammatory, neoplastic or hematologic disease
- Anemia (Hto<34% or Hb<10g/dl)
- Previous renal failure
- Previous treatment with oral iron supplement
- Minor stroke (NIHSS less than 4), lacunar or posterior territory
- Alcohol consumption (more than 40mg/Kg)
- Pregnancy
- Participation in other clinical trials