Therapeutic trial of repetitive transcranial magnetic stimulation after acute ischemic stroke

Completed

Phase N/A Results

Trial Description

To determine the possible effects of repeated daily motor cortex rTMS on recovery of movement in patients with hemiplegia.

Interventions

  • Electrical stimulation Other
    Intervention Desc: This category includes any form of electrical stimulation intended to improve motor function or pain after stroke.

Trial Design

Double-blind, randomized, single-center study.

Patient Involvement

All patients received standard physical and medical therapies (passive limb manipulation from the second day, increasing by the end of the first week to more active movements if patients improved function) plus anticoagulant low molecular weight heparin in the first week and then aspirin and notropic drugs.

Outcomes

Type Measure Time Frame Safety Issue
Primary Patients were assessed before and after treatment with Scandinavian Stroke Scale (SSS), NIH Stroke Scale (NIHSS), Barthel Index scale (BI), resting motor threshold (RMT) of healthy side, and motor evoked potentials (MEPs) of healthy and hemiplegic sides.

Sponsors

Medical Research Council, UK.