The Use of Transcranial Direct Current Stimulation (TDCS) to Enhance the Rehabilitative Effect of Vision Restoration Therapy


Phase 0 Results N/A

Eligibility Criteria

Inclusion Criteria

- Hemianopic field loss is defined as (a) visual field defect on the same side of visual space in both eyes as determined by monocular perimetry and (b) established structural damage of the post-charismatic visual system as documented by standard neuroimaging techniques (CT or MRI), medical reports, or a combination of these
- deep scotoma - defined field loss as confirmed by perimetry
- cognitive, language and motor function sufficient to understand the experiments and follow instructions
- informed written consent to participate in the study
- motivation to participate in the VRT program

Exclusion Criteria

- any sensory-motor loss other than visual
- ongoing use of CNS-active medications for an active neurological disease
- ongoing use of psychoactive medications, such as stimulants, antidepressants, and anti-psychotic medications for an active psychiatric condition
- presence of additional potential TDCS risk factors:
- Damaged skin at the site of stimulation (i.e., skin with ingrown hairs, acne, razor nicks, wounds that have not healed, recent scar tissue, broken skin, etc.)
- Presence of an electrically, magnetically or mechanically activated implant (including cardiac pacemaker), an intracerebral vascular clip, or any other electrically sensitive support system.
- Metal in any part of the body, including metal injury to the eye. (Jewelry must be removed during stimulation.)
- A history of medication-resistant epilepsy in the family
- Past history of seizures or unexplained spells of loss of consciousness