The SMARTChip Stroke Study

Active, not recruiting

Phase N/A Results N/A

Eligibility Criteria

Main study
Stroke patients:
Inclusion criteria:
- Aged 18 years or over
- Admitted to hospital with suspected stroke, diagnosed by a suitably qualified doctor or nurse using an appropriate clinical assessment (e.g. FAST, NIHSS, WHO criteria)
- Patient has ongoing symptoms of stroke at the time of enrolment in to the study.
Exclusion criteria:
- Onset of stroke symptoms >4.5 hours prior to admission or time of onset of symptoms is not known
- Patient has undergone thrombolysis during current admission (N.B. patients can be enrolled before planned thrombolysis, but not after)
- Patient's stroke symptoms have resolved completely prior to enrolment in the study
- The patient, or their consultee if the patient is incapacitated, is unwilling to provide written informed consent
Healthy controls
Inclusion criteria:
- Aged 18 years and over
- Scheduled for surgery
- Available for follow-up
Exclusion criteria:
- History of, or evidence of current, cerebrovascular disease, including stroke, transient ischaemic attack, subarachnoid haemorrhage and vascular dementia
- History of cardiovascular disease, including myocardial infarction, angina or peripheral vascular disease
- History of, or current, gout
- Currently receiving chemotherapy
- History of diabetes
- Unwilling or unable to provide written informed consent
Feeding Controls sub-study Inclusion criteria
- Aged 18 years and over
- Member of NHS staff
- Willing to eat the study meal provided (sandwich with a meat based filling)
Exclusion criteria
- Current acute health problems requiring medical review, investigation, or treatment
- History of, or evidence of current, cerebrovascular disease, including stroke, transient ischaemic attack, subarachnoid haemorrhage and vascular dementia
- History of cardiovascular disease, including myocardial infarction, angina or peripheral vascular disease
- History of, or current, gout
- Currently receiving chemotherapy
- History of diabetes
- Unwilling or unable to provide written informed consent
Spasticity sub-study
Stroke patients Inclusion criteria - Patients with suspected stroke, who have been enrolled on to the main study at UHNM
Exclusion criteria
- Unwilling or unable to provide written informed consent to the spasticity sub-study
Controls Inclusion criteria
- Aged 18 years and over
- Member of NHS staff
- Willing to complete follow-up visits
Exclusion criteria
- Current acute health problems requiring medical review, investigation, or treatment
- History of, or evidence of current, cerebrovascular disease, including stroke, transient ischaemic attack, subarachnoid haemorrhage and vascular dementia
- History of cardiovascular disease, including myocardial infarction, angina or peripheral vascular disease
- History of gout
- Currently receiving chemotherapy
- History of diabetes
- Unwilling or unable to provide written informed consent