The Secondary Prevention of Nonvalvular Atrial Fibrillation Patients With an Initial Cardioembolic Stroke "CE"


Phase 3 Results N/A

Eligibility Criteria

Inclusion Criteria

- Age 18 years or older.
- Stable condition within 14 days of oneset,Nonvalvular Atrial Fibrillation Patients With an Initial Cardioembolic Stroke
- Diagnosis need to conform to the Cardioembolic Stroke about clinical and neuroimaging and laboratory examination requirements.

Exclusion Criteria

- Mitral stenosis or previous valvular heart surgery
- Admission for acute coronary syndrome or percutaneous coronary intervention within 30 days
- Active infective endocarditis
- Purpura disease or blood coagulation disorder
- Active bleeding or bleeding tendency
- History of intracranial hemorrhage or other serious bleeding events
- Confirmed with peptic ulcer disease within 30 days
- Esophageal varices
- Major surgical procedure or trauma in the previous 30 days
- Persistent blood pressure 180/100 mm Hg or greater with or without antihypertensive treatment
- Requirement for chronic anticoagulant treatment for disorders other than atrial fibrillation
- Severe liver and kidney function
- Allergy for warfarin, aspirin and hirudin
- Child bearing potential, pregnancy, or lactation