The Norwegian Sonothrombolysis in Acute Stroke Study "NOR-SASS"

Terminated

Phase 2/3 Results N/A

Eligibility Criteria

Inclusion Criteria

- Ischemic stroke in the anterior circulation
- Treatment within 4.5 hours after stroke onset
- Informed consent

Exclusion Criteria

- Patients with premorbid modified Rankin Scale (mRS) score ≥3;
- Patients for whom a complete NIH Stroke Score cannot be obtained;
- Hemiplegic migraine with no arterial occlusion on baseline CT;
- Seizure at stroke onset and no visible occlusion on baseline CT;
- Intracranial haemorrhage on baseline CT;
- Clinical subarachnoid haemorrhage even if baseline CT is normal;
- Large areas of hypodense ischaemic changes on baseline CT;
- Patients with primary endovascular treatment;
- Female, pregnant or breast feeding; pericarditis; sepsis; any other serious medical illness likely to interact with treatment; confounding pre-existent neurological or psychiatric disease; unlikely to complete follow-up; any investigational drug <14 days;