The Evaluation of Safety, Tolerability and Pharmacokinetics/Pharmacodynamics of JPI-289 in Healthy Male Volunteers


Phase 1 Results N/A

Eligibility Criteria

Inclusion Criteria

- 19~55 years healthy male
- BMI measurement 20kg/m²~27kg/m²
- 90 ≤ SBP<140(mmHg) 60 ≤ DBP<100(mmHg) 45 ≤ Pulse rate<100(bpm)
- Signed the informed consent form to participate voluntarily and to comply with the trial requirements
- For a follow-up visit and during the study period, blood samples and availability

Exclusion Criteria

- History of clinically significant hepatic, gastrointestinal, pulmonary, musculoskeletal, endocrine, psychiatric, hematooncologic, cardiovascular (Specially asthma, obstructive pulmonary disease, peptic ulcer)
- History of skin disease of graft affecting absorption of the drug
- History of drug abuse
- Positive urine drug screening
- Administrated investigational product in a previous clinical trial within 60 days of the screening test
- Donated blood within 60 days prior to screening test