The Effects of tDCS Combined With Balance Training on Postural Control in Chronic Stroke Patients

Recruiting

Phase N/A Results N/A

Trial Description

Purpose:
The incidence of stroke in low-to-middle income countries is increasing .Balance impairment and falling negatively impact function of stroke patients. Mobility is based on successful postural control and about 30% of individuals with stroke are unable to ambulate without assistance.Transcranial direct current stimulation (tDCS) is a new promising tool for motor recovery in neurological disease.This can be addressed through a tDCS intervention.
Objective:The objectives of this study is to examine the efficacy of anodal tDCS combined with Biodex balance training on postural control in chronic stroke patients using laboratory and clinical assessments. The following essential treatment components; a) active tDCS stimulation paired with Biodex balance training, b)sham tDCS paired with Biodex balance training program.
To identify combinations effects of tDCS stimulation plus balance training . Hypothesis: Anodal tDCS targeting leg motor area (CZ) for 5-days plus Biodex balance training, will significantly improve stroke clients' balance and functional mobility.
Double blinded sham -controlled randomized tDCS stimulation Arms Assigned Interventions
Experimental: Arm 1
tDCS brain stimulation and simultaneous balance training
Participants underwent Active tDCS brain stimulation (20 minutes) and simultaneous balance training(20 minutes) for 5 consecutive days.
No Intervention: Arm 2 Sham tDCS brain stimulation (20 minutes) and simultaneous balance training

Detailed Description

Participants underwent tDCS(2mA) brain stimulation (20 minutes) and simultaneous balance training(20 minutes) for 5 consecutive days, All outcome measures will be measured in 4 time points: pre-test, post-test after 10 sessions of intervention, and after 1 week and 1 months post intervention as follow ups.

Conditions

Interventions

  • Sham Device
    Intervention Desc: During sham stimulation, the current ramped up for 30 seconds, ramped back down for 30 seconds, and then remained off for the duration of the stimulation then and simultaneous balance training(20 minutes) for 5 consecutive days,for 1 week.
    ARM 1: Kind: Experimental
    Label: ARM 2
    Description: ARM2: Sham tDCS and the 5 days balance training Will be offered
  • Transcranial direct current stimulation (tDCS) Device
    Other Names: tDCS; Low intensity transcranial DC stimulator; Soterix 1x1
    Intervention Desc: Participants underwent tDCS(2mA) brain stimulation (20 minutes) and simultaneous balance training(20 minutes) for 5 consecutive days,for 1 week.
    ARM 1: Kind: Experimental
    Label: Transcranial direct current stimulation
    Description: ARM1: Transcranial direct current stimulation (tDCS) intervention and simultaneous balance training. Participants underwent tDCS(2mA) brain stimulation (20 minutes) and simultaneous balance training(20 minutes) for 5 consecutive days,for 1 week.
  • Trance cranial direct current stimulation (tDCS) Device
    Intervention Desc: Participants underwent tDCS(2mA) brain stimulation (20 minutes) and simultaneous balance training(10-15 minutes) for 5 consecutive days,for 1 week.
    ARM 1: Kind: Experimental
    Label: tDCS(2mA)
    Description: ARM1: Trance cranial direct current stimulation (tDCS) intervention and simultaneous balance training. Participants underwent tDCS(2mA) brain stimulation (20 minutes) and simultaneous balance training(10-15 minutes) for 5 consecutive days,for 1 week.

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Investigator)
  • Purpose: Treatment
  • Intervention: Parallel Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary postural control 1 week after Completion of intervention No
Secondary Spasticity outcome measure 1 week after Completion of intervention No
Secondary Static Balance After 5 days Yes
Secondary Change of Static Balance 1 week Yes

Sponsors