The Effect of Repetitive Transcranial Magnetic Stimulation for Poststroke Dysphagia Recovery

Recruiting

Phase 2 Results N/A

Trial Description

Dysphagia is one of severe complications among stroke survivors. Dysphagia is usually associated with high levels of morbidity, mortality, and financial cost. In recent years, repetitive transcranial magnetic stimulation (rTMS) has shown promise to facilitate poststroke dysphagia. However, most researches were preliminary studies in the past. The present study aims to investigate the immediate and long-term efficacy of high frequency rTMS on chronic dysphagic patients.

Detailed Description

rTMS protocol: 5 Hz real or sham stimulation, 10 minutes per day, for 10 week-days.

Conditions

Interventions

  • RTMS, Magstim Rapid2 Device
    Intervention Desc: 5 Hz rTMS
    ARM 1: Kind: Experimental
    Label: Real 5 Hz rTMS
    Description: real 5 Hz rTMS, 10 minutes per day, for 10 weekdays.
    ARM 2: Kind: Experimental
    Label: sham 5 Hz rTMS
    Description: sham 5Hz rTMS, 10 minutes per day, for 10 weekdays.

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Outcomes Assessor)
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Parallel Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary Dysphagia severity on Aus TOMs swallowing score up to 3 months No
Secondary Imaging evidence with video-esophagography up to 3 months No

Sponsors