The Dutch Acute Stroke Trial (DUST): Prediction of Outcome With Computed Tomography (CT) - Perfusion and CT-angiography "DUST"


Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- Acute neurological deficit caused by cerebral ischaemia
- Admission < 9 hours after onset of neurological deficit
- NIH Stroke Scale (NIHSS) of at least 2
- No absolute contraindications against intravenous contrast
- Informed consent from patient or family after admission scan
- Patients who awaken with stroke symptoms can only be included if they went to sleep without any stroke symptoms and the time from going to sleep until imaging is less than 9 hours

Exclusion Criteria

- Neurological deficit caused by another diagnosis than cerebral ischaemia (such as intracerebral hemorrhage, subarachnoid hemorrhage or tumor)
- Patients with known contrast allergy or kidney failure
- Patients with the known combination of renal insufficiency and heart failure (New York Heart Association (NYHA) IV) will be excluded for the CTP and CTA scan at 3 days; they will have a non-contrast CT (NCCT) at that time.