The Carotid and Middle Cerebral Artery Occlusion Surgery Study "CMOSS"


Phase 3 Results N/A

Summary of Purpose

The recently published Carotid Occlusion Surgery Study (COSS) failed to show a benefit of extracranial-intracranial (EC-IC) bypass surgery over medical therapy in patients with symptomatic hemodynamically significant carotid occlusion. Since then on, different controversies have been raised on several aspects including the study population, qualifications of surgeons and hemodynamic evaluation. In COSS...

Read More →

Trial Milestones

The following dates are available for this trial. Trial information last updated on 31 December 2012.

1 Dec 2012 24 Dec 2012 1 Dec 2016 1 Dec 2017 1 Dec 2012 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Single Blind (Outcomes Assessor)
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment