The Austrian Paradoxical Cerebral Embolism Trial "TACET"

Completed

Phase N/A Results

Results

Results of TACET suggest a non-significantly (p=0.144) lower frequency of patients suffering from recurrent cerebrovascular events after transcatheter closure compared with conservative treatment, 16 patients experienced recurrences (5 with stroke, 11 with TIA) during conservative secondary prevention compared to 4 patients (all TIA) after transcatheter closure. Only the one patient with angiographically confirmed pulmonary fistula had 2 stroke recurrences. Interventional therapy was associated with a highly successful (99.1%) implantation rate and with a periinterventional complication rate of 13.6% (all reversible).