Tenecteplase Versus Alteplase Before Endovascular Therapy for Ischemic Stroke "EXTEND-IA TNK"

Completed

Phase 2 Results N/A

Summary of Purpose

Patients presenting to the emergency department with acute ischemic stroke, who are are eligible for standard intravenous tPA therapy within 4.5 hours of stroke onset will be assessed for major vessel occlusion to determine their eligibility for randomization into the trial. If the patient gives informed consent they will be randomised 50:50 using central computerised allocation to intravenous alteplase or...

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 28 March 2018.

23 Mar 2015 9 Mar 2015 16 Oct 2017 1 Feb 2018 1 Mar 2018 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Open Label
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment

Contacts