tDCS and Physical Therapy in Stroke


Phase 2 Results N/A

Eligibility Criteria

Inclusion Criteria

- First time clinical ischemic or hemorrhagic cerebrovascular accident (radiologically confirmed)
- Demonstrates adequate balance while wearing a hand restraint on the unaffected arm
- Ability to stand from a sitting position and ability to stand with or without upper extremity support
- Stroke onset at least 6 months prior to study enrollment

Exclusion Criteria

- Significant pre-stroke disability
- Any substantial decrease in alertness, language reception, or attention that might interfere with understanding instructions for motor testing
- Excessive pain in any joint of the paretic extremity
- A terminal medical diagnosis consistent with survival of less than 1 year
- Advanced liver, kidney, cardiac, or pulmonary disease
- Coexistent major neurological or psychiatric disease (including epilepsy)
- A history of significant alcohol or drug abuse in the prior 3 years
- Use of neuropsychotropic drugs - such as antidepressants
- Patients may not be actively enrolled in a separate intervention study targeting stroke recovery
- Patients may not have already received constraint-induced movement therapy and/or tDCS treatment for stroke