tDCS and Motor Training and Motor Deficit After Stroke

Completed

Phase 3 Results N/A

Eligibility Criteria

Inclusion Criteria

- diagnosis of stroke made by clinical features and documented by neuroimaging studies (CT or MRI scans
- stroke duration > 12 months
- severe hand deficit at stroke onset (Medical Research Council grade <2) and
- subsequently recovered to the level moderate hand deficit with presence of hand movements evaluated by the Fugl-Meyer upper-extremity Assessment (FMA) of Motor Recovery after Stroke between 28-50 points (max. 66 pts),
- spasticity between 0-2 assessed on the Modified Ashworth Scale

Exclusion Criteria

- any clinically significant or unstable medical disorder,
- diagnosis od major depression,
- diagnosis odf substance or alcohol abuse or any neurological disorder other than stroke, including neglect, aphasia, hemianopsia and serious cognitive impairment (Mini-Mental State Examination < 24).
- any contraindications to tDCS, including histories of seizure, cerebral aneurysm, and prior surgery involving metallic implants