Swiss Intravenous and Intra-arterial Thrombolysis for Treatment of Acute Ischemic Stroke Registry "SWISS"

Completed

Phase N/A Results N/A

Eligibility Criteria

Inclusion Criteria

- Age ≥ 18 years
- Intracranial arterial occlusion confirmed by conventional angiography, MRA or CTA
- National Institute of health Stroke Scale (NIHSS) score ≥ 4 or isolated aphasia or hemianopia
- Time to treatment < 6 hours
Exclusion Criteria
- Intracranial haemorrhage on CT scn or MRI
- History of intracranial haemorrhage or subarachnoid haemorrhage
- Platelet count < 100'000
- International normalized ration (INR) > 1.5
- Partial thromboplastin time (PTT) > 1.5 times the normal value
- Known hereditary of acquired haemorrhagic diathesis
- Pre-existing neurological deficit (mRS>2)
- Previous stroke that might interfere with the neurological assessment (mRS >2)
- Active gastric ulcer
- Major trauma within the preceding 3 months
- Major surgery within the past 4 weeks
- Childbirth within the previous 4 weeks
- Pregnancy
- Uncontrolled hypertension (>185/10 on repeated measures despite antihypertensive medication)
- Severe systemic disease with poor prognosis (e.g. cancer, severe heart failure)
- Intracranial neoplasm
- Combined IVT and IAT
- Combined Intravenous and Ultrasound Thrombolysis