Study to Develop a Reliable Nomogram That Incorporates Clinical and Genetic Information


Phase N/A Results

Eligibility Criteria

Inclusion Criteria

1. Age ≥ 18 years old
2. Any newly diagnosed condition that will require treatment with therapeutic doses of warfarin for at least 4-6 weeks, e.g. deep venous thrombosis (DVT), pulmonary embolism (PE), atrial fibrillation (AF), orthopedic surgery, etc.
3. Written informed consent

Exclusion Criteria

1. Current treatment with warfarin
2. Contraindication to therapeutic anticoagulation:
- Active major bleeding
- History of intracranial bleeding
- Surgery, delivery, organ biopsy within 3 days
- Gastrointestinal bleeding within 10 days
- Major trauma within 3 days
- Head injury requiring hospitalization within 3 months
- Intracranial tumor
- Neurosurgery or ophthalmologic surgery within the past month
3. Life expectancy < 3 months
4. Pregnancy