Study on the Efficacy of Alprostadil Injection in Patients With Acute Ischemic Stroke

Not yet recruiting

Phase 4 Results N/A

Eligibility Criteria

Inclusion Criteria

1. ischemic stroke diagnosed by CT or MRI
2. Age: 18-75 years
3. Pre-stroke mRS score is 0-1
4. within 72 hours symptoms onset
5. 4 ≤ NIHSS <20
6. Patient is willing to participate voluntarily and to sign a written patient informed consent

Exclusion Criteria

1. intracranial tumors, encephalitis or lesions diagnosed by CT or MRI
2. patients with thrombolytic therapy
3. low platelet , blood system diseases or other bleeding tendency
4. suspected subarachnoid hemorrhage or aortic dissection coma
5. atrial fibrillation, myocardial infarction, heart valve disease, infective endocarditis, heart rate <50 beats / min
6. ALT or AST continued to rise more than 3 times the upper limit of normal creatinine clearance rate<30ml/min
7. Dementia and mental illness
8. Patient who is participating in other trials or has been participated in other trials in recent 3 months