Study of the Effect of Transcranial Stimulations in Aphasic Subject Within a Year of Their Stroke

Not yet recruiting

Phase N/A Results N/A

Trial Description

The aim of this work is to study the effect of transcranial direct current stimulation combined with naming therapy in acute and post-acute stroke comparing four bihemispheric positioning electrodes to a sham condition.

Detailed Description

TDCS have shown a positive effect on clinical outcome in naming treatment in aphasic subjects however some aspects as the positioning of the electrodes on the head are still unclear. That is why we compare the effects of four different positionings of the electrodes (two anterior over Broca's area and its homologue and two posterior over Wernicke's area and its homologue) to a sham stimulation in order to observe if a more important effect of one or another positioning could be found.

Conditions

Interventions

  • Eldith DC-stimulator, configuration F7A Device
    Intervention Desc: tDCS will be delivered during a 20 minutes speech-language therapy session
    ARM 1: Kind: Experimental
    Label: F7A
    Description: Anodal electrode set on the left Broca's area and cathodal electrode set on its right homologue. Active stimulation.
  • Eldith DC-stimulator, configuration F7C Device
    Intervention Desc: tDCS will be delivered during a 20 minutes speech-language therapy session
    ARM 1: Kind: Experimental
    Label: F7C
    Description: Cathodal electrode set on the left Broca's area and anodal electrode set on its right homologue. Active stimulation.
  • Eldith DC-stimulator, configuration T5A Device
    Intervention Desc: tDCS will be delivered during a 20 minutes speech-language therapy session
    ARM 1: Kind: Experimental
    Label: T5A
    Description: Anodal electrode set on the left Wernicke's area and cathodal electrode set on its right homologue. Active stimulation.
  • Eldith DC-stimulator, configuration T5C Device
    Intervention Desc: tDCS will be delivered during a 20 minutes speech-language therapy session
    ARM 1: Kind: Experimental
    Label: T5C
    Description: Cathodal electrode set on the left Wernicke's area and anodal electrode set on its right homologue. Active stimulation.
  • Eldith DC-stimulator, configuration Sham Device
    Intervention Desc: Sham tDCS will be delivered during a 20 minutes speech-language therapy session
    ARM 1: Kind: Experimental
    Label: Sham
    Description: Electrodes set on the left Broca's area and its right homologue or electrodes set on the left Wernicke's area and its right homologue, but no stimulation will be delivered.

Trial Design

  • Allocation: Randomized
  • Masking: Double Blind (Subject, Caregiver)
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Single Group Assignment

Outcomes

Type Measure Time Frame Safety Issue
Primary Percentage of improvement of picture naming Before stimulation and immediately after stimulation No

Sponsors