Study of NeuroAid In Enhancing Recovery After Stroke "TIERS"


Phase 2 Results N/A

Eligibility Criteria

Inclusion Criteria

- Subject had cerebral infarction confirmed by Computed Tomography (CT scan or Magnetic Resonance Imaging (MRI) imaging
- Presents within 1 month after stroke onset
- Presents with motor power of from grade 1 - 4/5 in at least one limb
- Has a pre-stroke modified Rankin score ≤ 1.
- Age between 21 and 80 years old
- Female subjects are eligible to participate in the trial if they are of non childbearing potential (hysterectomy or post-menopausal)
- Subject or legally acceptable representative is willing and able to provide written informed consent
- Subject and carer are willing and able to comply with investigational drug administration schedule.

Exclusion Criteria

- Subject has received thrombolysis
- Subject has evidence of intra-cerebral hemorrhage on brain CT scan or MRI
- Subject has definite indication for full-dose or long-term anticoagulation therapy
- Subject has other significant non-ischemic brain lesion which could affect function disability
- Subject has co-existing systemic diseases: terminal cancer, renal failure (creatinine >200 μmol/L, if known), cirrhosis, severe dementia or psychosis
- Subject has a history of previous stroke/s
- Subject has participated in another clinical trial within the last three months
- Subject has aphasia or any other cognitive disabilities which prevent cooperation with study instructions
- Subject has dense hemiplegia (grade 0 motor power)
- Subject has haemoglobin level of <10mg/dl on admission
- Subject has a history of craniotomy or seizures