Study of Carotid Occlusion and Neurocognition


Phase N/A Results N/A

Summary of Purpose

To determine the relationship between cognitive functioning and blood flow in the brain among patients randomized to either extracranial-intracranial (EC-IC) bypass or medical therapy alone in the Carotid Occlusion Surgery Study (COSS).

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 29 July 2013.

1 Nov 2004 17 Oct 2006 1 Jun 2012 1 Jun 2012 1 Jul 2013 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Single Blind (Outcomes Assessor)
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Parallel Assignment


  • Randolph S Marshall, MD 212 305 8389