Structurally Reorganizing Motor Cortex in Stroke Patients Through Hebbian-type Stimulation


Phase N/A Results

Eligibility Criteria

Inclusion Criteria

- Age 18-85
- Single cerebral ischemic infarction > 6 month affecting the primary motor output system of the hand at a cortical (M1) level as defined by MRI of the brain
- At the time of cerebral infarct a motor deficit of hand of MRC of <4- of wrist and finger extension/flexion movement
- Good recovery of hand function as defined by MRC of 4 or 4+ of wrist- and finger extension/flexion movements
- Ability to perform wrist extension movements
- No other neurological disorder
- No intake of CNS active drugs
- Ability to give informed consent
- Ability to meet criteria of inclusion experiment
- No major cognitive impairment
- No contraindication to TMS or MRI