Stroke With Transfusions Changing to Hydroxyurea

Terminated

Phase 3 Results

Summary of Purpose

The purpose of this study is to compare standard therapy (transfusions and chelation) with alternative therapy (hydroxyurea and phlebotomy) for the prevention of secondary stroke and management of iron overload in children with sickle cell anemia (SCA). Trial Stopped: The study has been stopped due to safety and futility concerns.

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 14 January 2013.

1 Oct 2006 20 Jul 2005 1 Jun 2010 1 Dec 2010 1 Aug 2012 28 Dec 2011
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Open Label
  • Purpose: Prevention
  • Endpoint: Efficacy Study
  • Intervention: Parallel Assignment

Contacts

Not available