Stroke Prevention in Sickle Cell Anemia (STOP 1)


Phase 3 Results

Summary of Purpose

To reduce episodes of first time stroke by 75 percent in children with sickle cell anemia by the administration of prophylactic transfusion therapy.

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 21 December 2015.

1 Jul 1994 27 Oct 1999 Unavailable 1 Aug 2000 1 Nov 2005 Unavailable
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Purpose: Prevention


  • Donald J. Brambilla New England Research Institute Watertown, Massachusetts