Stroke Imaging Package Study "SIPS"

Completed

Phase N/A Results N/A

Trial Description

Our study aims to explore the value of new imaging technique package in predicting early neurological deterioration (END) as well as 90-day unfavorable outcome in patients with acute ischaemic stroke.

Detailed Description

1. Patients with acute ischemic stroke within 4.5-72h after onset were prospectively enrolled in our study and underwent standerdized clinical and new imaging technique package assessment.
2. New imaging technique package mainly includes conventional cranial MRI ´╝łT1,T2,T2 FLAIR,DWI, and ADC), cranial magnetic resonance angiography (MRA), and intracranial vessel wall imaging (High-Resolution Magnetic Resonance Imaging,HRMRI) as well as susceptibility weighted imaging (SWI).
3. The neurofunctional fluctuation during hospitalization as well as 90-day outcomes were carefully assessed. Patients were followed up for 90-days after stroke onset.
4. Our study aims to explore the value of new imaging technique package in predicting early neurological deterioration (END) as well as 90-day unfavorable outcome in patients with acute ischaemic stroke.

Conditions

Trial Design

  • Observation: Cohort
  • Perspective: Prospective
  • Sampling: Non-Probability Sample

Trial Population

Patients will be recruited from the collaborative stroke centers and will be followed for the duration of their hospitalization. Patients will be followed up until at least 3 months after stroke onset.

Outcomes

Type Measure Time Frame Safety Issue
Primary association between stroke classification and stroke deterioration and recurrence two years No
Primary association between imaging-based markers and stroke deterioration and recurrence two years No
Primary early neurological deterioration within 3 weeks after stroke onset (END-3 weeks) 3 weeks after stroke onset
Primary 90-days prognosis 90-days after stroke onset

Sponsors