STRATAGEM: Strategy for Managing Antiplatelet Therapy in the Perioperative Period of Non Coronary Surgery "STRATAGEM"


Phase 4 Results N/A

Eligibility Criteria

Inclusion Criteria

- Written informed consent
- Patients over eighteen years of age
- Patients treated with oral antiplatelet agents for secondary prevention (i.e. established and symptomatic cardiovascular disease):
- regardless of the reason (coronary artery disease, stroke or TIA [transient ischemic attack], peripheral arterial disease)
- regardless of the antiplatelet agent (aspirin, clopidogrel, ticlopidine, dipyridamole).
- Patients scheduled for intermediate or high-risk surgery, including but not limited to:
- any long procedure associated with hemodynamic variations or major blood loss
- valvular surgery
- thoracic surgery
- orthopedic surgery
- general (intraperitoneal) surgery
- urological surgery
- vascular surgery
- ear, nose, and throat (ENT) cancerology-related surgery.

Exclusion Criteria

- Coronary bypass grafting surgery
- History of thrombocytopenia or allergy to heparin
- Arterial stent placement within the previous 30 days
- Active bleeding
- Formal contraindication to the use of anticoagulants and aspirin
- Recent acute coronary syndrome
- Ophthalmological surgery (posterior chamber)
- Neurosurgery
- Emergency surgery
- Thrombotic or bleeding risk deemed unacceptable by the surgical and anesthetic team
- Pregnancy