Statin treatment withdrawal in ischemic stroke


Phase N/A Results


60% of the statin withdrawl group showed a higher frequency of mRS score > 2 at the end of the 90-day follow-up period, compared to 39% of the atorvastatin group (p = 0.043). For early neurologic deterioration (END) the rate was 65.2% versus 20.9% (p < 0.0001), and rate of greater infarct volume was 74 [45, 126] vs 26 [12, 70] mL; p = 0.002. Statin withdrawal was associated with a 4.66–fold increase in the risk of death or dependency, a 8.67–fold increase in the risk of END, and an increase in mean infarct volume of 37.63 mL.