Standard Treatment with Alteplase to Reverse Stroke study "STARS"


Phase N/A Results

Trial Description

To assess the safety, clinical outcome, and adverse events in patients treated with intravenous tPA for acute stroke.


Trial Design

Prospective, multicenter study of 389 patients at 57 medical centers in the United States.


Type Measure Time Frame Safety Issue
Primary Time intervals between stroke symptom onset, hospital arrival, and treatment with tPA; pretreatment computed tomographic scan results, intracerebral hemorrhage, and major systemic bleeding. The modified Rankin Scale score was used to assess clinical outcomes at 30 days.