SMARTCap Stroke Study: A Field Deployable Blood Test for Stroke "SMARTCAP"

Completed

Phase N/A Results N/A

Update History

21 Apr '16
The Summary of Purpose was updated.
New
The hypothesis is that a stroke causes release of purines from brain into blood and that this is a very early biomarker of brain ischaemia. The investigators propose a simple blood test of substances (the purines) that result from cellular metabolism and are produced in excess when brain cells are starved of oxygen and glucose (as occurs during a stroke).
Old
The hypothesis is that a stroke causes release of purines from brain into blood and that this is a very early biomarker of brain ischaemia. The investigators propose a simple blood test of substances (the purines) that result from cellular metabolism and are produced in excess when brain cells are starved of oxygen and glucose (as occurs during a stroke).
The eligibility criteria were updated.
New
Inclusion Criteria: 1. Stroke patients: Admitted to the Hyperacute Stroke Unit having a suspected stroke within 1 hour of admission. Important to note that not all these patients will have suffered a stroke 2. Control participants: Relatives of patients admitted to the stroke treatment pathway, who are healthy and have no signs of cardiovascular illness 3. Healthy volunteers Exclusion Criteria: 1. Stroke patients: Delay in admission exceeds the time window of 4 hours between stroke symptoms and admission 2. Control participants: Obvious signs or history of cerebrovascular disease 3. Unhealthy volunteers
Old
Inclusion Criteria: 1. Stroke patients: Admitted to the Hyperacute Stroke Unit having a suspected stroke within 1 hour of admission. Important to note that not all these patients will have suffered a stroke 2. Control participants: Relatives of patients admitted to the stroke treatment pathway, who are healthy and have no signs of cardiovascular illness 3. Healthy volunteers Exclusion Criteria: 1. Stroke patients: Delay in admission exceeds the time window of 4 hours between stroke symptoms and admission 2. Control participants: Obvious signs or history of cerebrovascular disease 3. Unhealthy volunteers
10 Sep '15
A location was updated in Coventry.
New
The overall status was removed for University Hospitals Coventry & Warwickshire NHS Trust.
A location was updated in Stoke-on-Trent.
New
The overall status was removed for University of Keele.