To compare the frequency of new cerebral ischemic lesions after carotid endarterectomy (CEA) or carotid artery stenting (CAS) for symptomatic stenosis of the internal carotid artery, and to test their impact on cognitive function and quality of life.
- Endarterectomy, carotid (CEA)Procedure/Surgery
Intervention Desc: Surgical therapy to remove atherosclerotic plaque in narrowed carotid arteries.
- Stent, carotid Procedure/Surgery
Intervention Desc: Intravascular procedure to maintain carotid artery patency
Multicenter substudy of a randomized controlled trial - ICSS.
Patients will be randomized to receive either carotid endarterectomy (CEA) or carotid artery stenting (CAS)
|Type||Measure||Time Frame||Safety Issue|
|Primary||Detailed neuropsychological examination and Stroke-Specific Quality of Life Scale will be given in the week preceding the intervention, and at six months thereafter.|
|Secondary||Stroke-Specific Quality of Life Scale at six months, and ischemic damage as assessed with MRI at one day and one month.|