Silent Cerebral Infarct Transfusion Multi-Center Clinical Trial "SIT"


Phase 3 Results

Summary of Purpose

The goal of this study is to determine the effectiveness of blood transfusion therapy for prevention of silent cerebral infarct (stroke) in children with sickle cell anemia.

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Trial Milestones

The following dates are available for this trial. Trial information last updated on 7 January 2016.

1 Dec 2004 10 Nov 2003 1 Dec 2013 1 Dec 2013 1 Jan 2016 4 May 2015
Start Date First Received 1st Completion Completion Verification Results

Trial Design

  • Allocation: Randomized
  • Masking: Single Blind (Investigator)
  • Purpose: Treatment
  • Endpoint: Efficacy Study
  • Intervention: Parallel Assignment


  • Cindy Terrill, CCRP Washington University School of Medicine St. Louis, Missouri USA 314-286-1169