Schlaganfallkonsortium Rhein-Neckar (Stroke Consortium Rhine-Neckar) "FAST"

Not yet recruiting

Phase N/A Results N/A

Trial Description

FAST is an investigator-initiated multicenter study embedded in a German multistate acute stroke network. The main objectives of the FAST study are to improve outcomes and quality of care for stroke patients, to quantify the number of patients in need of thrombectomy within an integrated stroke network, to study the best way of delivering and performing thrombectomy and to investigate the best model of pre-hospital selection and referral for stroke patients.

Detailed Description

Since 2015, mechanical thrombectomy in patients with large vessel occlusion has become an evidence based highly efficient treatment. In contrast to thrombolysis, thrombectomy can only be delivered by qualified interventionalists at comprehensive stroke centers. Thus, the implementation of thrombectomy into clinical practice remains a challenge. We aim to establish a population based approach within a patient registry in a federal state overarching regional stroke network covering over 4 million inhabitants and integrating approximately 30 hospitals with different levels of expertise. The registry will include data from all acute ischemic stroke patients - approx. 12.000 patients p.a - within the network. We plan to establish a central multi-interface platform integrating clinical data from the prehospital, intrahospital and rehabilitation phase including mandatory quality assurance, neurological and neuroradiological treatment and outcome data. The registry will allow addressing important questions, such as how many patients are candidates for thrombectomy, how many resources are needed to meet that demand and how treatment procedures and times can be improved. The overarching aim is to deliver high quality stroke care to every patient in the region.

Conditions

Interventions

  • Not applicable (observational study) Other
    Intervention Desc: Observational study without study related intervention
    ARM 1: Kind: Experimental
    Label: Primary CSC admission
    Description: Patients with primary admission to endovascular-ready hospital (comprehensive stroke center)
    ARM 2: Kind: Experimental
    Label: Primary non-CSC SU admission
    Description: Patients with primary admission to non-endovascular-ready hospital with (regional/local) stroke unit
    ARM 3: Kind: Experimental
    Label: Non-acute stroke hospital admission
    Description: Patients with primary admission to non-acute stroke-ready hospital

Trial Population

Acute stroke patients admitted to one of the hospitals of the Stroke Consortium Rhein-Neckar (FAST)

Outcomes

Type Measure Time Frame Safety Issue
Primary Number of patients receiving thrombectomy 24h after stroke symptom onset
Primary Functional outcome after 3 months

Sponsors