Safty and Feasibility Study of Therapeutic Cooling in Acute Ischemic Stroke (COOLAID ├śresund)

Completed

Phase 2 Results N/A

Eligibility Criteria

Inclusion Criteria

- National Institute of Health Stroke Scale (NIHSS) score on admission between 5 and 18
- Inclusion within 24 hours after stroke onset
- Diagnosis of ischemic stroke verified by MRI, CT or CTP adjudicated by including physician
- Informed consent from patient or proxy

Exclusion Criteria

- Modified ranking scale (mRS)>2 indicating significant disability before onset of stroke
- MRI or CT evidence for massive ischemic damage (>50% Middle cerebral artery (MCA) territory)
- Severe concomitant diseases such as heart failure, chronic obstructive lung disease or known cancer
- Presently on anticoagulation treatment
- No informed consent from patient or proxy