Safety Study of Dantrolene in Subarachnoid Hemorrhage


Phase 1/2 Results



  • Salomone S, Soydan G, Moskowitz MA, Sims JR. Inhibition of cerebral vasoconstriction by dantrolene and nimodipine. Neurocrit Care. 2009;10(1):93-102. Epub 2008 Oct 16. Pubmed ID:18923817
  • Muehlschlegel S, Rordorf G, Bodock M, Sims JR. Dantrolene mediates vasorelaxation in cerebral vasoconstriction: a case series. Neurocrit Care. 2009;10(1):116-21. Epub 2008 Aug 12. Pubmed ID:18696267
  • Muehlschlegel S, Sims JR. Dantrolene: mechanisms of neuroprotection and possible clinical applications in the neurointensive care unit. Neurocrit Care. 2009;10(1):103-15. Epub 2008 Aug 12. Review. Pubmed ID:18696266
  • Muehlschlegel S, Rordorf G, Sims J. Effects of a single dose of dantrolene in patients with cerebral vasospasm after subarachnoid hemorrhage: a prospective pilot study. Stroke. 2011 May;42(5):1301-6. Epub 2011 Mar 31. Pubmed ID:21454813

Sources for Trial Information