Safety and Efficacy of Low-dose Heparin During Intracranial Angioplasty and Stent Placement "SELHIAS "


Phase N/A Results

Eligibility Criteria

Inclusion Criteria

1. 18-75 years of age 2. Recurrent ischemic events (transient ischemic attack and/or stroke) attributed to an intracranial stenosis ? 50% at digital subtraction angiography (DSA) 3. Performed intracranial angioplasty and stent placement

Exclusion Criteria

1. Intracranial hemorrhage and major ischemic stroke (NIHSS ?8) in the same hemisphere as the target lesion within 6 weeks 2. Concurrent severe extracranial artery stenosis and angioplasty and stent placement needed to be performed 3. Concurrent intracranial tumors, cerebral AVM and aneurysms 4. History of heparin allergy 5. Received perioperative heparin or surgical procedures requiring systemic heparinization 6. Preoperative platelet or coagulation abnormalities 7. Patients were not eligible if they could not cooperate with the study procedures or provide informed consent