To generate a database of clinical information regarding patients treated with tissue plasminogen activator (tPA) within 3 hours of acute stroke.
- Tissue plasminogen activator (Activase®)Drug
Other Names: Alteplase; tPA Intervention Desc: Thrombolytic
International register of tPA-treated stroke patients. Data will be used in the SITS-MOST trial.
Patients will be treated according to their clinician's discretion.
|Type||Measure||Time Frame||Safety Issue|
|Primary||SITS-ISTR is a register. Data will be entered into the registry regarding the time delay between symptom onset and treatment initiation, age, gender, stroke risk factors, stroke subtype, imaging before and after treatment (CT- measured infarct volume, MRI with optional PWI-DWI mismatch, and transcranial Doppler sonography), National Institutes of Health Stroke Scale (NIHSS) score 1 and 24 hours after treatment, tPA dosage, global effects, hemorrhagic events, stroke etiology, and modified Rankin scale (MRS) score at 3 months.|