Safe Implementation of Thrombolysis in Stroke International Stroke Thrombolysis Register "SITS-ISTR"

Active, not recruiting

Phase N/A Results

Trial Description

To generate a database of clinical information regarding patients treated with tissue plasminogen activator (tPA) within 3 hours of acute stroke.

Interventions

Trial Design

International register of tPA-treated stroke patients. Data will be used in the SITS-MOST trial.

Patient Involvement

Patients will be treated according to their clinician's discretion.

Outcomes

Type Measure Time Frame Safety Issue
Primary SITS-ISTR is a register. Data will be entered into the registry regarding the time delay between symptom onset and treatment initiation, age, gender, stroke risk factors, stroke subtype, imaging before and after treatment (CT- measured infarct volume, MRI with optional PWI-DWI mismatch, and transcranial Doppler sonography), National Institutes of Health Stroke Scale (NIHSS) score 1 and 24 hours after treatment, tPA dosage, global effects, hemorrhagic events, stroke etiology, and modified Rankin scale (MRS) score at 3 months.

Sponsors

Boehringer-Ingelheim