Rosuvastatin Versus Atorvastatin in the Treatment of Hypercholesterolaemia in African American Subjects(ARIES) "ARIES"

Completed

Phase 3 Results N/A

Trial Description

The purpose of this study is to compare the effect of 6 weeks of treatment with Rosuvastatin with 6 weeks of treatment with Atorvastatin in African American subjects with hypercholesterolemia.

Conditions

Interventions

  • Atorvastatin (LipitorĀ®)Drug
    Other Names: Lipitor
    ARM 1: Kind: Experimental
    Label: 2
    Description: Atorvastatin
  • Rosuvastatin (Crestor)Drug
    ARM 1: Kind: Experimental
    Label: 1
    Description: Rosuvastatin

Trial Design

  • Allocation: Randomized
  • Masking: Open Label
  • Purpose: Treatment
  • Endpoint: Safety/Efficacy Study
  • Intervention: Parallel Assignment

Patient Involvement

Patient randomized to either Rosuvastatin or Atorvastatin for six weeks. Cholesterol levels done at baseline and 6 weeks for changes.

Outcomes

Type Measure Time Frame Safety Issue
Primary Low density lipoproteins cholesterol levels.
Secondary Other blood lipid level changes; safety: adverse events & abnormal laboratory markers
Primary Low density lipoproteins cholesterol levels 6 weeks
Secondary Other blood lipid level changes 6 weeks
Secondary Safety: adverse events & abnormal laboratory markers 6 weeks

Sponsors