Role of the Right Brain in Recovery of Language Function in Chronic Stroke

Completed

Phase N/A Results N/A

Eligibility Criteria

INCLUSION CRITERIA:
We will include patients with thromboembolic non-hemorrhagic hemispheric lesions and with hemorrhagic hemispheric lesions (as documented by CT or MRI) at least 12 months after the stroke.
We will choose subjects with chronic stable aphasia, that initially presented with severe aphasia and have partially recovered.
Assessment of the initial functional state will be taken either from patient report or medical records. All of the aphasic patients are already known to the investigators from the NIDCD.
EXCLUSION CRITERIA - HEALTHY CONTROLS:
Unable to perform the task (naming of everyday objects in less than 10 s).
History of alcohol or drug abuse or psychiatric illness like depression.
Epilepsy.
Are less than 18 years of age.
Pregnant or breast feeding a child.
EXCLUSION CRITERIA - PATIENTS:
Unable to perform the task (naming of everyday objects in less than 10 s).
History of alcohol or drug abuse or psychiatric illness like depression.
Epilepsy.
Are less than 18 years of age.
Pregnant or breast feeding a child.
Patients with cerebellar or brainstem lesions.
Patients or subjects with severe uncontrolled medical problems (e.g. cardiovascular disease, severe rheumatoid arthritis, active joint deformity of arthritic origin, active cancer or renal disease, any kind of end-stage pulmonary or cardiovascular disease).
Patients or subjects with increased intracranial pressure as evaluated by clinical means.
Individuals receiving drugs acting primarily on the central nervous system.